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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF11 All Species: 16.67
Human Site: S812 Identified Species: 22.92
UniProt: P52732 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52732 NP_004514.2 1056 119159 S812 N G N L E K I S Q E T E Q R C
Chimpanzee Pan troglodytes XP_507923 1056 119132 S812 N G N L E K I S Q E T E K R C
Rhesus Macaque Macaca mulatta XP_001087644 853 96218 L628 L Q E R I N V L K T D L L T S
Dog Lupus familis XP_534964 1334 149091 S1094 N S N L E V V S Q E T E Q R C
Cat Felis silvestris
Mouse Mus musculus Q6P9P6 1052 118008 S811 N S N L E T V S Q E I T Q K C
Rat Rattus norvegicus O55165 796 89797 E571 L R D E E T M E L R G T Y S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 A839 E L R S A Q I A D L Q Q K L L
Frog Xenopus laevis P28025 1060 119314 S816 T S S I N T I S Q E S Q Q W C
Zebra Danio Brachydanio rerio NP_775368 955 106984 N730 E L V Q C L Q N Q M N L L A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46863 1066 121145 N819 Q V H M K N L N Q K Y E K E T
Honey Bee Apis mellifera XP_623508 706 80766 S481 D V A N I V T S D V N K L H D
Nematode Worm Caenorhab. elegans P46873 699 78760 A474 K T Q K L A A A L N V H K D D
Sea Urchin Strong. purpuratus P46872 699 78679 Q474 N E K L N A I Q K K L I V G G
Poplar Tree Populus trichocarpa XP_002314206 1066 119757 H819 I K A E W T V H M E K T E S N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 G805 A E N E A R E G A D F S A A K
Baker's Yeast Sacchar. cerevisiae P28742 1111 125776 N853 L P I N E F L N K I S Q T I C
Red Bread Mold Neurospora crassa P48467 928 102392 T703 I A L K N S E T E H L K A L V
Conservation
Percent
Protein Identity: 100 99.8 77.5 69.3 N.A. 79.7 23.3 N.A. N.A. 25.3 56.2 47.7 N.A. 33.5 37.1 27.4 29.2
Protein Similarity: 100 99.9 79 73.8 N.A. 89 40.4 N.A. N.A. 43.5 72.7 63.9 N.A. 55.4 52 42.5 42.8
P-Site Identity: 100 93.3 0 80 N.A. 60 6.6 N.A. N.A. 6.6 40 6.6 N.A. 13.3 6.6 0 20
P-Site Similarity: 100 100 13.3 86.6 N.A. 73.3 20 N.A. N.A. 33.3 66.6 13.3 N.A. 60 20 13.3 33.3
Percent
Protein Identity: 32.9 N.A. N.A. 31.9 27.2 27.5
Protein Similarity: 52.3 N.A. N.A. 51.5 48.6 45.5
P-Site Identity: 6.6 N.A. N.A. 6.6 13.3 0
P-Site Similarity: 20 N.A. N.A. 20 46.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 12 0 12 12 6 12 6 0 0 0 12 12 0 % A
% Cys: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 36 % C
% Asp: 6 0 6 0 0 0 0 0 12 6 6 0 0 6 12 % D
% Glu: 12 12 6 18 36 0 12 6 6 36 0 24 6 6 0 % E
% Phe: 0 0 0 0 0 6 0 0 0 0 6 0 0 0 0 % F
% Gly: 0 12 0 0 0 0 0 6 0 0 6 0 0 6 6 % G
% His: 0 0 6 0 0 0 0 6 0 6 0 6 0 6 0 % H
% Ile: 12 0 6 6 12 0 30 0 0 6 6 6 0 6 0 % I
% Lys: 6 6 6 12 6 12 0 0 18 12 6 12 24 6 6 % K
% Leu: 18 12 6 30 6 6 12 6 12 6 12 12 18 12 6 % L
% Met: 0 0 0 6 0 0 6 0 6 6 0 0 0 0 0 % M
% Asn: 30 0 30 12 18 12 0 18 0 6 12 0 0 0 6 % N
% Pro: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 6 6 6 6 0 6 6 6 42 0 6 18 24 0 0 % Q
% Arg: 0 6 6 6 0 6 0 0 0 6 0 0 0 18 0 % R
% Ser: 0 18 6 6 0 6 0 36 0 0 12 6 0 12 12 % S
% Thr: 6 6 0 0 0 24 6 6 0 6 18 18 6 6 6 % T
% Val: 0 12 6 0 0 12 24 0 0 6 6 0 6 0 12 % V
% Trp: 0 0 0 0 6 0 0 0 0 0 0 0 0 6 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 6 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _